GR 103691 (Standard)
GR 103691 (Standard) is the analytical standard of GR 103691. This product is intended for research and analytical applications. GR 103691 is a potent, selective dopamine D3 receptor antagonist with a Ki value of 0.4 nM. GR 103691 shows more than 100-fold selectivity for human dopamine human (h) D3 over hD4 and hD1 sites[1].
Product Specifications
CAS Number
162408-66-4
Target
Dopamine Receptor; Reference Standards
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
O=C(C1=CC=C(C2=CC=C(C(C)=O)C=C2)C=C1)NCCCCN3CCN(C4=CC=CC=C4OC)CC3
Molecular Formula
C30H35N3O3
Molecular Weight
485.62
References & Citations
[1]Audinot V, et al. A comparative in vitro and in vivo pharmacological characterization of the novel dopamine D3 receptor antagonists (+) -S 14297, nafadotride, GR 103,691 and U 99194. J Pharmacol Exp Ther. 1998 Oct;287 (1) :187-97.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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