2-Methylthio-ATP (tetrasodium)

2-Methylthio-ATP tetrasodium is a non-specific P2-receptor agonist. 2-Methylthio-ATP tetrasodium causes noncompetitive inhibition of ADP-induced human platelet aggregation[1].

Product Specifications

CAS Number

[100020-57-3]

UNSPSC

12352005

Target

Others

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Purity

98.0

Solubility

H2O : 50 mg/mL (ultrasonic)

Smiles

O[C@H]([C@@H]1O)[C@](O[C@@H]1CO[P](O[P](O[P](O[Na])(O[Na])=O)(O[Na])=O)(O[Na])=O)([H])N2C3=NC(SC)=NC(N)=C3N=C2

Molecular Formula

C11H14N5Na4O13P3S

Molecular Weight

641.20

References & Citations

[1]N. J. Cusack, et al. Specific but noncompetitive inhibition by 2-alkylthio analogues of adenosine 5'-monophosphate and adenosine 5'-triphosphate of human platelet aggregation induced by adenosine 5'-diphosphate. Br J Pharmacol. 1982 Feb; 75 (2) : 397��400.|[2]S G Hamilton, et al. The effects of inflammation and inflammatory mediators on nociceptive behaviour induced by ATP analogues in the rat. Br J Pharmacol. 1999 Jan;126 (1) :326-32.