QX-314 (bromide) (Standard)
QX-314 (bromide) (Standard) is the analytical standard of QX-314 (bromide) (HY-101350) . This product is intended for research and analytical applications. QX-314 bromide is a membrane-impermeable permanently charged sodium channel blocker[1].
Product Specifications
CAS Number
[24003-58-5]
Target
Reference Standards; Sodium Channel
Related Pathways
Membrane Transporter/Ion Channel; Others
Field of Research
Neurological Disease
Smiles
O=C(NC1=C(C)C=CC=C1C)C[N+](CC)(CC)CC.[Br-]
Molecular Formula
C16H27BrN2O
Molecular Weight
343.30
References & Citations
[1]Rivera-Acevedo RE, et al. The quaternary lidocaine derivative, QX-314, exerts biphasic effects on transient receptor potential vanilloid subtype 1 channels in vitro. Anesthesiology. 2011 Jun;114 (6) :1425-34.|[2]Binshtok AM, et al. Coapplication of lidocaine and the permanently charged sodium channel blocker QX-314 produces a long-lasting nociceptive blockade in rodents. Anesthesiology. 2009 Jul;111 (1) :127-37.|[3]Talbot MJ, et al. Intracellular QX-314 inhibits calcium currents in hippocampal CA1 pyramidal neurons. J Neurophysiol. 1996 Sep;76 (3) :2120-4.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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