AH 11110A
AH 11110A is an α1B-adrenoceptor antagonist, but it can't effectively distinguish between the different subtypes of alpha (1) adrenoceptors (A, B, and D), nor can it clearly differentiate between alpha (1) and alpha (2) adrenoceptors[1][2].
Product Specifications
CAS Number
179388-65-9
UNSPSC
12352005
Target
Adrenergic Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease; Cardiovascular Disease
Smiles
OC(CC(N1CCCCC1)=N)COC2=C(C3=CC=CC=C3)C=CC=C2.Cl
Molecular Formula
C21H27ClN2O2
Molecular Weight
374.90
References & Citations
[1]M Eltze, et al. Failure of AH11110A to functionally discriminate between alpha (1) -adrenoceptor subtypes A, B and D or between alpha (1) - and alpha (2) -adrenoceptors. Eur J Pharmacol. 2001 Mar;415 (2-3) :265-76.|[2]Hua Zhang, et al. Different alpha-adrenoceptors mediate migration of vascular smooth muscle cells and adventitial fibroblasts in vitro. Am J Physiol Heart Circ Physiol. 2002 Jun;282 (6) :H2364-70.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
α adrenergic receptor
Available Sizes
Frequently Asked Questions
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