AH 11110A

AH 11110A is an α1B-adrenoceptor antagonist, but it can't effectively distinguish between the different subtypes of alpha (1) adrenoceptors (A, B, and D), nor can it clearly differentiate between alpha (1) and alpha (2) adrenoceptors[1][2].

Product Specifications

CAS Number

[179388-65-9]

UNSPSC

12352005

Target

Adrenergic Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease; Cardiovascular Disease

Smiles

OC(CC(N1CCCCC1)=N)COC2=C(C3=CC=CC=C3)C=CC=C2.Cl

Molecular Formula

C21H27ClN2O2

Molecular Weight

374.90

References & Citations

[1]M Eltze, et al. Failure of AH11110A to functionally discriminate between alpha (1) -adrenoceptor subtypes A, B and D or between alpha (1) - and alpha (2) -adrenoceptors. Eur J Pharmacol. 2001 Mar;415 (2-3) :265-76.|[2]Hua Zhang, et al. Different alpha-adrenoceptors mediate migration of vascular smooth muscle cells and adventitial fibroblasts in vitro. Am J Physiol Heart Circ Physiol. 2002 Jun;282 (6) :H2364-70.