β-Secretase Inhibitor IV (Standard)
β-Secretase Inhibitor IV (Standard) is the analytical standard of β-Secretase Inhibitor IV (HY-10133) . This product is intended for research and analytical applications. β-Secretase Inhibitor IV is a potent, cell-active BACE-1 inhibitor with IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively.
Product Specifications
CAS Number
[797035-11-1]
Target
Beta-secretase; Reference Standards
Related Pathways
Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
O=S(N(C)C1=CC(C(N[C@@H](CC2=CC=CC=C2)[C@H](O)CNC3CC3)=O)=CC(C(N[C@H](C)C4=CC=CC=C4)=O)=C1)(C)=O
Molecular Formula
C31H38N4O5S
Molecular Weight
578.72
References & Citations
[1]Pietrak BL, et al. Biochemical and cell-based assays for characterization of BACE-1 inhibitors. Anal Biochem. 2005 Jul 1;342 (1) :144-51.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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