AHN 1-055 (hydrochloride) (Standard)

AHN 1-055 (hydrochloride) (Standard) is the analytical standard of AHN 1-055 (hydrochloride) (HY-101315) . This product is intended for research and analytical applications. AHN 1-055 hydrochloride is a dopamine uptake inhibitor, with an IC50 of 71 nM. AHN 1-055 hydrochloride binds with high affinity to the dopamine transporter (DAT) [1].

Product Specifications

CAS Number

[202646-03-5]

Target

Dopamine Transporter; Reference Standards

Related Pathways

Neuronal Signaling; Others

Field of Research

Neurological Disease

Smiles

CN1[C@@H]2C[C@@H](OC(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)C[C@H]1CC2.Cl

Molecular Formula

C21H24ClF2NO

Molecular Weight

379.87

References & Citations

[1]Sangeeta R, et, al. Investigation of the potential pharmacokinetic and pharmaco-dynamic drug interaction between AHN 1-055, a potent benztropine analog used for cocaine abuse, and cocaine after dosing in rats using intracerebral microdialysis. Biopharm Drug Dispos. 2006 Jul; 27 (5) : 229-40.