SYM 2081 (Standard)
SYM 2081 (Standard) is the analytical standard of SYM 2081. This product is intended for research and analytical applications. SYM 2081 is a kainate receptor agonist. SYM 2081 is a substrate of EAAT1 (Km of 54 μM). SYM 2081 inhibits EAAT2-mediated glutamate transport (Kb is 3.4 μM in Xenopus oocytes), modulates Apoptotic signaling pathways (increases Bcl-2 and decreases Bax/caspase-3 expression). SYM 2081 exhibits neuroprotective activity. SYM 2081 can be used in the study of hypoxic-ischemic brain damage and inflammatory or neuropathic pain[1][2][3][4].
Product Specifications
CAS Number
31137-74-3
Target
Bcl-2 Family; Caspase; EAAT; iGluR; Reference Standards
Related Pathways
Apoptosis; Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Smiles
N[C@@H](C[C@@H](C)C(O)=O)C(O)=O
Molecular Formula
C6H11NO4
Molecular Weight
161.16
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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