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DMU2139 (Standard)

DMU2139 (Standard) is the analytical standard of DMU2139. This product is intended for research and analytical applications. DMU2139 is a potent and specific CYP1B1 inhibitor, with IC50s of 9 nM and 795 nM for CYP1B1 and CYP1A1, respectively.

Product Specifications

CAS Number

1821143-80-9

Target

Cytochrome P450; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Smiles

O=C(C1=CC=C2C=C(OC)C=CC2=C1)/C=C/C3=CC=CN=C3

Molecular Formula

C19H15NO2

Molecular Weight

289.33

References & Citations

[1]Horley NJ, et al. Discovery and characterization of novel CYP1B1 inhibitors based on heterocyclic chalcones: Overcoming cisplatin resistance in CYP1B1-overexpressing lines. Eur J Med Chem. 2017 Mar 31;129:159-174.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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