DMU2105 (Standard)
DMU2105 (Standard) is the analytical standard of DMU2105 (HY-101284) . This product is intended for research and analytical applications. DMU2105 is a potent and specific CYP1B1 inhibitor, with IC50s of 10 nM and 742 nM for CYP1B1 and CYP1A1, respectively.
Product Specifications
CAS Number
[1821143-79-6]
Target
Cytochrome P450; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Smiles
O=C(C1=CC=CN=C1)/C=C/C2=CC=C3C=CC=CC3=C2
Molecular Formula
C18H13NO
Molecular Weight
259.31
References & Citations
[1]Horley NJ, et al. Discovery and characterization of novel CYP1B1 inhibitors based on heterocyclic chalcones: Overcoming cisplatin resistance in CYP1B1-overexpressing lines. Eur J Med Chem. 2017 Mar 31;129:159-174.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-101284R/
Scientific Category
Reference Standards
Curated Selection
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