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(R) -VU 6008667 (Standard)

(R) -VU 6008667 (Standard) is the analytical standard of (R) -VU 6008667. This product is intended for research and analytical applications. (R) -VU 6008667, the less active (R) -enantiomer to VU 6008667, is devoid of M5 NAM activity (IC50>10 μM).

Product Specifications

CAS Number

2097818-14-7

Target

MAChR; Reference Standards

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Neurological Disease

Smiles

O=C1N2[C@](N(C(C3=CC=C(F)C(F)=C3)=O)CC2)(C4=CC=C(Cl)C(C)=C4)C5=C1C=CC=C5

Molecular Formula

C24H17ClF2N2O2

Molecular Weight

438.85

References & Citations

[1]McGowan KM et al, Continued optimization of the M5 NAM ML375: Discovery of VU6008667, an M5 NAM with high CNS penetration and a desired short half-life in rat for addiction studies. Bioorg Med Chem Lett. 2017 Mar 15;27 (6) :1356-1359.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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