(R) -VU 6008667 (Standard)
(R) -VU 6008667 (Standard) is the analytical standard of (R) -VU 6008667 (HY-101281B) . This product is intended for research and analytical applications. (R) -VU 6008667, the less active (R) -enantiomer to VU 6008667, is devoid of M5 NAM activity (IC50>10 μM) [1].
Product Specifications
CAS Number
[2097818-14-7]
Target
MAChR; Reference Standards
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
O=C1N2[C@](N(C(C3=CC=C(F)C(F)=C3)=O)CC2)(C4=CC=C(Cl)C(C)=C4)C5=C1C=CC=C5
Molecular Formula
C24H17ClF2N2O2
Molecular Weight
438.85
References & Citations
[1]McGowan KM et al, Continued optimization of the M5 NAM ML375: Discovery of VU6008667, an M5 NAM with high CNS penetration and a desired short half-life in rat for addiction studies. Bioorg Med Chem Lett. 2017 Mar 15;27 (6) :1356-1359.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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