CHMFL-BMX-078 (Standard)
CHMFL-BMX-078 (Standard) is the analytical standard of CHMFL-BMX-078. This product is intended for research and analytical applications. CHMFL-BMX-078 is a highly potent and selective type II irreversible BMX kinase inhibitor with an IC50 of 11 nM.
Product Specifications
CAS Number
1808288-51-8
Target
BMX Kinase; Reference Standards
Related Pathways
Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C(C1=CN=C(NC2=CC=C(C)C(NC(C=C)=O)=C2)N=C1NC)NC3=CC(NC(C4=CC(OC)=C(OC)C(OC)=C4)=O)=CC=C3C
Molecular Formula
C33H35N7O6
Molecular Weight
625.67
References & Citations
[1]Liang X, et al. Discovery of 2- ((3-Acrylamido-4-methylphenyl) amino) -N- (2-methyl-5- (3,4,5-trimethoxybenzamido) phenyl) -4- (methylamino) pyrimidine-5-carboxamide (CHMFL-BMX-078) as a Highly Potent and Selective Type II Irreversible Bone Marrow Kinase in the X Chromosome (BMX) Kinase Inhibitor. J Med Chem. 2017 Mar 9;60 (5) :1793-1816.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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