ODQ (Standard)
ODQ (Standard) is the analytical standard of ODQ. This product is intended for research and analytical applications. ODQ is a potent and selective soluble guanylyl cyclase (sGC, nitric oxide-activated enzyme) inhibitor. ODQ enhances the pro-apoptotic effects of Cisplatin in human mesothelioma cells[1].
Product Specifications
CAS Number
41443-28-1
UNSPSC
12352005
Target
Apoptosis; Guanylate Cyclase; Reference Standards
Related Pathways
Apoptosis; GPCR/G Protein; Others
Field of Research
Cancer
Smiles
O=C1ON=C2N1C3=C(C=CC=C3)N=C2
Molecular Formula
C9H5N3O2
Molecular Weight
187.16
References & Citations
[1]Ronald Fiscus, et al. ODQ, an inhibitor of soluble guanylyl cyclase (nitric oxide-activated enzyme), enhances the pro-apoptotic effects of cisplatin in human mesothelioma cells. Cancer Res May 1 2007 (67) (9 Supplement) LB-43.|[2]Zacharowski K, et al. The selective guanylate cyclase inhibitor ODQ reduces multiple organ injury in rodent models of Gram-positive and Gram-negative shock. Crit Care Med. 2001;29 (8) :1599-1608.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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