Agmatine-d8 (sulfate)

Agmatine-d8 sulfate is a deuterium labeled Agmatine sulfate (HY-101238) . Agmatine sulfate exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide synthesis. It is an endogenous agonist at imidazoline receptor and a NO synthase inhibitor[1][2][3].

Product Specifications

CAS Number

[909556-32-7]

UNSPSC

12352211

Target

Endogenous Metabolite; Imidazoline Receptor; Isotope-Labeled Compounds; NO Synthase

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; Others

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease

Smiles

O=S(O)(O)=O.N=C(N)NC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])N

Molecular Formula

C5H8D8N4O4S

Molecular Weight

236.32

References & Citations

[1]Li G, et al. Agmatine: an endogenous clonidine-displacing substance in the brain. Science. 1994 Feb 18;263 (5149) :966-9.|[2]Reis DJ, et al. Is agmatine a novel neurotransmitter in brain? Trends Pharmacol Sci. 2000 May;21 (5) :187-93. |[3]Galea E, et al. Inhibition of mammalian nitric oxide synthases by agmatine, an endogenouspolyamine formed by decarboxylation of arginine. Biochem J. 1996 May 15;316 (Pt 1) :247-9.