(Rac) -Silodosin

(Rac) -Silodosin ((Rac) -KAD 3213) is the racemate of Silodosin (HY-10122) . Silodosin is a potent, selective and orally active α1A-adrenergic receptor (α1A-AR) blocker[1].

Product Specifications

CAS Number

[160970-64-9]

Product Name Alternative

(Rac) -KAD 3213; (Rac) -KMD 3213

UNSPSC

12352005

Target

Adrenergic Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Endocrinology

Smiles

O=C(C1=CC(CC(NCCOC2=CC=CC=C2OCC(F)(F)F)C)=CC3=C1N(CCCO)CC3)N

Molecular Formula

C25H32F3N3O4

Molecular Weight

495.53

References & Citations

[1]Zhao F, et, al. Design, Synthesis, and Biological Evaluation of Indoline and Indole Derivatives as Potent and Selective α1A-Adrenoceptor Antagonists. J Med Chem. 2016 Apr 28;59 (8) :3826-39.