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PSB-12054

PSB-12054 is a selective P2X4 antagonist with an IC50 of 0.189 μM at human P2X4 receptors. PSB-12054 can be used in the research of neuropathic pain and neurodegenerative diseases[1].

Product Specifications

CAS Number

[1407632-07-8]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

P2X Receptor

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Neurological Disease

Smiles

O=C(OCC=1C=CC=CC1)N2C=3C=CC=CC3OC=4C=CC=CC42

Molecular Formula

C20H15NO3

Molecular Weight

317.34

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

References & Citations

[1]Hernandez-Olmos V, et al. N-substituted phenoxazine and acridone derivatives: structure-activity relationships of potent P2X4 receptor antagonists. J Med Chem. 2012 Nov 26;55 (22) :9576-88.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

P2X4 Receptor

Available Sizes

Curated Selection

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