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BI 689648 (Standard)

BI 689648 (Standard) is the analytical standard of BI 689648. This product is intended for research and analytical applications. BI 689648 is a novel, highly selective aldosterone synthase inhibitor which can inhibit CYP11B1 and CYP11B2 with IC50s of 310 and 2.1 nM, respectively.

Product Specifications

CAS Number

1633009-87-6

Target

Cytochrome P450; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Endocrinology

Smiles

O=C(N1CCCC2=C1N=CC(C3=CC(COC)=CN=C3)=C2)N

Molecular Formula

C16H18N4O2

Molecular Weight

298.34

References & Citations

[1]Weldon SM, et al. Selectivity of BI 689648, a Novel, Highly Selective Aldosterone Synthase Inhibitor: Comparison with FAD286 and LCI699 in Nonhuman Primates. J Pharmacol Exp Ther. 2016 Oct;359 (1) :142-50.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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