Evobrutinib (Standard)

Evobrutinib (Standard) is the analytical standard of Evobrutinib (HY-101215) . This product is intended for research and analytical applications. Evobrutinib (M2951) is an orally active, potent, highly selective and irreversibly covalent BTK inhibitor, with an IC50 of 8.9 nM. Evobrutinib (M2951) can be used for the research of autoimmune diseases[1].

Product Specifications

CAS Number

[1415823-73-2]

Target

Btk; Reference Standards

Related Pathways

Others; Protein Tyrosine Kinase/RTK

Field of Research

Inflammation/Immunology; Cancer

Smiles

C=CC(N1CCC(CNC2=NC=NC(N)=C2C3=CC=C(OC4=CC=CC=C4)C=C3)CC1)=O

Molecular Formula

C25H27N5O2

Molecular Weight

429.51

References & Citations

[1]Caldwell R, et al. Discovery of Evobrutinib: An Oral, Potent and Highly Selective, Covalent Bruton's Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases. J Med Chem. 2019 Aug 1.