Fadraciclib (Standard)
Fadraciclib (Standard) is the analytical standard of Fadraciclib. This product is intended for research and analytical applications. Fadraciclib (CYC065) is a second-generation, orally available ATP-competitive inhibitor of CDK2/CDK9 kinases[1] with IC50s of 5 and 26 nM, respectively[2].
Product Specifications
CAS Number
1070790-89-4
Target
CDK; Reference Standards
Related Pathways
Cell Cycle/DNA Damage; Others
Field of Research
Cancer
Smiles
C[C@@H](O)[C@@H](NC1=NC(NCC2=C(C)C=C(C)N=C2)=C3N=CN(C(C)C)C3=N1)CC
Molecular Formula
C21H31N7O
Molecular Weight
397.52
References & Citations
[1]Cocco E, et al. Dual CCNE1/PIK3CA targeting is synergistic in CCNE1-amplified/PIK3CA-mutated uterine serous carcinomas in vitro and in vivo. Br J Cancer. 2016 Jul 26;115 (3) :303-11.|[2]Sumana Devata, et al. Molecular markers and venous thromboembolism (VTE) in acute myelogenous leukemia (AML)
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC940334-500 1x 500 µL
Cytokeratin 8 (H1), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC881757-100 1x 100 µL
CELA3B / ELA3B (Pancreatic Function Marker) (CELA3B/1757), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC742383-100 1x 100 µL
CD40 / TNFRSF5 / CD40L-Receptor (C40/2383), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 