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Tin protoporphyrin IX dichloride (Standard)

Tin protoporphyrin IX dichloride (Standard) is the analytical standard of Tin protoporphyrin IX dichloride. This product is intended for research and analytical applications. Tin protoporphyrin IX dichloride (SnPPIX) is a potent Heme oxygenase-1 (HO-1) inhibitor. Tin protoporphyrin IX dichloride sensitizes pancreatic ductal adenocarcinoma (PDAC) tumors to chemotherapy in mice model[1].

Product Specifications

CAS Number

14325-05-4

Target

Reactive Oxygen Species (ROS) ; Reference Standards

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Field of Research

Cancer

Smiles

[Cl-][Sn+4]123([N-]4C5=C(CCC(O)=O)C(C)=C4C=C(C(C=C)=C6C)[N]1=C6C=C(C(C=C)=C7C)[N-]2C7=CC(C(C)=C8CCC(O)=O)=[N]3C8=C5)[Cl-]

Molecular Formula

C34H32Cl2N4O4Sn

Molecular Weight

750.26

References & Citations

[1]Abdalla MY, et al.Enhancing responsiveness of pancreatic cancer cells to gemcitabine treatment under hypoxia by heme oxygenase-1 inhibition.Transl Res. 2019 May;207:56-69.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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