THK5351 (Standard)

THK5351 (Standard) is the analytical standard of THK5351 (HY-101183) . This product is intended for research and analytical applications. THK5351 can be radiolabeled and used as a radiotracer for in vivo imaging of tau pathology in the brain.

Product Specifications

CAS Number

[1707147-26-9]

Target

Reference Standards; Tau Protein

Related Pathways

Neuronal Signaling; Others

Field of Research

Neurological Disease

Smiles

O[C@@H](COC1=CC=C2N=C(C3=CC=C(NC)N=C3)C=CC2=C1)CF

Molecular Formula

C18H18FN3O2

Molecular Weight

327.35

References & Citations

[1]Harada R, et al. 18F-THK5351: A Novel PET Radiotracer for Imaging Neurofibrillary Pathology in Alzheimer Disease. J Nucl Med. 2016 Feb;57 (2) :208-14.|[2]Ishiki A, et al. Tau imaging with [18 F]THK-5351 in progressive supranuclear palsy. Eur J Neurol. 2017 Jan;24 (1) :130-136.