RS 23597-190 (Standard)
RS 23597-190 (Standard) is the analytical standard of RS 23597-190. This product is intended for research and analytical applications. RS 23597-190 (EP-A-501322) is a high affinity and selective 5-HT4 receptor antagonist. RS 23597-190 inhibits Serotonin (HY-B1473A) -induced tachycardia. RS 23597-190 significantly inhibits superoxide production in high glucose[1][2].
Product Specifications
CAS Number
149719-06-2
Target
5-HT Receptor; Reference Standards
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Cardiovascular Disease
Smiles
O=C(OCCCN1CCCCC1)C2=CC(Cl)=C(N)C=C2OC.Cl
Molecular Formula
C16H24Cl2N2O3
Molecular Weight
363.28
References & Citations
[1]Eglen RM, et al. RS 23597-190: a potent and selective 5-HT4 receptor antagonist. Br J Pharmacol. 1993 Sep;110 (1) :119-26.|[2]Du Y, et al. Adrenergic and serotonin receptors affect retinal superoxide generation in diabetic mice: relationship to capillary degeneration and permeability. FASEB J. 2015 May;29 (5) :2194-204.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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