RS 23597-190 (Standard)

RS 23597-190 (Standard) is the analytical standard of RS 23597-190 (HY-101172) . This product is intended for research and analytical applications. RS 23597-190 (EP-A-501322) is a high affinity and selective 5-HT4 receptor antagonist. RS 23597-190 inhibits Serotonin (HY-B1473A) -induced tachycardia. RS 23597-190 significantly inhibits superoxide production in high glucose[1][2].

Product Specifications

CAS Number

[149719-06-2]

Target

5-HT Receptor; Reference Standards

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Cardiovascular Disease

Smiles

O=C(OCCCN1CCCCC1)C2=CC(Cl)=C(N)C=C2OC.Cl

Molecular Formula

C16H24Cl2N2O3

Molecular Weight

363.28

References & Citations

[1]Eglen RM, et al. RS 23597-190: a potent and selective 5-HT4 receptor antagonist. Br J Pharmacol. 1993 Sep;110 (1) :119-26.|[2]Du Y, et al. Adrenergic and serotonin receptors affect retinal superoxide generation in diabetic mice: relationship to capillary degeneration and permeability. FASEB J. 2015 May;29 (5) :2194-204.