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Propargyl-PEG5-acid (Standard)

Propargyl-PEG5-acid (Standard) is the analytical standard of Propargyl-PEG5-acid (HY-101157) . This product is intended for research and analytical applications. Propargyl-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG5-acid can used to synthesize ADC inhibitors of Galectin-3. Propargyl-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG5-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[1245823-51-1]

Target

ADC Linker; PROTAC Linkers; Reference Standards

Related Pathways

Antibody-drug Conjugate/ADC Related; Others; PROTAC

Field of Research

Cancer

Smiles

O=C(O)CCOCCOCCOCCOCCOCC#C

Molecular Formula

C14H24O7

Molecular Weight

304.34

References & Citations

[1]Zhang H, et al. Thiodigalactoside-Bovine Serum Albumin Conjugates as High-Potency Inhibitors of Galectin-3: An Outstanding Example of Multivalent Presentation of Small Molecule Inhibitors. Bioconjug Chem. 2018 Apr 18;29 (4) :1266-1275.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

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