SG3199-Val-Ala-PAB (Standard)

SG3199-Val-Ala-PAB (Standard) is the analytical standard of SG3199-Val-Ala-PAB (HY-101152) . This product is intended for research and analytical applications. SG3199-Val-Ala-PAB is an intermediate of Tesirine synthesis. Tesirine is a agent-linker conjugate for ADC which can be used for the research of several cancers[1].

Product Specifications

CAS Number

[1595275-61-8]

Target

Drug-Linker Conjugates for ADC; Reference Standards

Related Pathways

Antibody-drug Conjugate/ADC Related; Others

Field of Research

Cancer

Smiles

O=C(NC1=CC=C(COC(N2[C@@H](O)[C@@](CC(C)=C3)([H])N3C(C4=CC(OC)=C(OCCCCCOC5=C(OC)C=C6C(N7[C@](CC(C)=C7)([H])C=NC6=C5)=O)C=C42)=O)=O)C=C1)[C@H](C)NC([C@H](C(C)C)N)=O

Molecular Formula

C49H59N7O11

Molecular Weight

922.03

References & Citations

[1]Tiberghien AC, et, al. Design and Synthesis of Tesirine, a Clinical Antibody-Drug Conjugate Pyrrolobenzodiazepine Dimer Payload. ACS Med Chem Lett. 2016 May 24;7 (11) :983-987.