KI696 isomer (Standard)
KI696 isomer (Standard) is the analytical standard of KI696 isomer. This product is intended for research and analytical applications. KI696 isomer is the less active isomer of KI696 (HY-101140). KI696 is a high affinity probe that disrupts the Keap1/NRF2 interaction[1].
Product Specifications
CAS Number
1799974-69-8
Target
Keap1-Nrf2; Reference Standards
Related Pathways
NF-κB; Others
Field of Research
Metabolic Disease; Inflammation/Immunology
Smiles
COC1=C(N2C)C(N=N2)=CC([C@@H](C3=CC(CN(C[C@H]4C)S(=O)(C5=CC=CC=C5O4)=O)=C(C)C=C3)CC(O)=O)=C1
Molecular Formula
C28H30N4O6S
Molecular Weight
550.63
References & Citations
[1]Davies TG, et al. Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery. J Med Chem. 2016 Apr 28;59 (8) :3991-4006.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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