TP-3654 (Standard)
TP-3654 (Standard) is the analytical standard of TP-3654 (HY-101126) . This product is intended for research and analytical applications. TP-3654 is a second-generation Pim kinase inhibitor with Ki values of 5 and 42 nM for Pim-1 and Pim-3, respectively.
Product Specifications
CAS Number
[1361951-15-6]
Target
Pim; Reference Standards
Related Pathways
JAK/STAT Signaling; Others
Field of Research
Cancer
Smiles
OC(C)(C)[C@H]1CC[C@H](NC2=NN3C(C=C2)=NC=C3C4=CC=CC(C(F)(F)F)=C4)CC1
Molecular Formula
C22H25F3N4O
Molecular Weight
418.46
References & Citations
[1]Foulks JM, et al. A small-molecule inhibitor of PIM kinases as a potential treatment for urothelial carcinomas. Neoplasia. 2014 May;16 (5) :403-12.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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