UCM 608 (Standard)

UCM 608 (Standard) is the analytical standard of UCM 608 (HY-101074) . This product is intended for research and analytical applications. UCM 608 is a high affinity melatonin (MT) membrane receptor agonist. The pKi values for MT1 and MT2 are 10.7 and 10.4[1][2].

Product Specifications

CAS Number

[151889-03-1]

Target

Melatonin Receptor; Reference Standards

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Smiles

CC(NCCC1=C(C2=CC=CC=C2)NC3=C1C=C(OC)C=C3)=O

Molecular Formula

C19H20N2O2

Molecular Weight

308.37

References & Citations

[1] Radogna F, et al. Rapid and transient stimulation of intracellular reactive oxygen species by melatonin in normal and tumor leukocytes. Toxicol Appl Pharmacol. 2009;239 (1) :37-45.|[2]Mor, M., et al. Synthesis, pharmacological characterization and QSAR studies on 2-substituted indole melatonin receptor ligands. Bioorganic & Medicinal Chemistry, 9 (4), 1045–1057.