Fmoc-leucine (Standard)
Fmoc-leucine (Standard) is the analytical standard of Fmoc-leucine (HY-101064) . This product is intended for research and analytical applications. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-induced glucose-intolerant, and in diabetic db/db mice. Fmoc-leucine has a lower adipogenic activity[1].
Product Specifications
CAS Number
[35661-60-0]
Target
PPAR; Reference Standards
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease
Smiles
CC(C)C[C@@H](C(O)=O)NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O
Molecular Formula
C21H23NO4
Molecular Weight
353.42
References & Citations
[1]Rocchi S, et al. A unique PPARgamma ligand with potent insulin-sensitizing yet weak adipogenic activity. Mol Cell. 2001 Oct;8 (4) :737-47.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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