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Brensocatib (Standard)

Brensocatib (Standard) is the analytical standard of Brensocatib. This product is intended for research and analytical applications. Brensocatib (AZD7986) is an oral dipeptidyl peptidase 1 (DPP1) inhibitor with pIC50s of 6.85, 7.6, 7.7, 7.8, and 7.8 in human, mouse, rat, dog and rabbit, respectively[1].

Product Specifications

CAS Number

1802148-05-5

Target

Dipeptidyl Peptidase; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Inflammation/Immunology

Smiles

O=C([C@H]1OCCCNC1)N[C@H](C#N)CC2=CC=C(C3=CC=C(OC(N4C)=O)C4=C3)C=C2

Molecular Formula

C23H24N4O4

Molecular Weight

420.46

References & Citations

[1]Doyle K, et al. Discovery of Second Generation Reversible Covalent DPP1 Inhibitors Leading to an Oxazepane Amidoacetonitrile Based Clinical Candidate (AZD7986) . J Med Chem. 2016 Oct 27;59 (20) :9457-9472.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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