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Src Inhibitor 1 (Standard)

Src Inhibitor 1 (Standard) is the analytical standard of Src Inhibitor 1. This product is intended for research and analytical applications. Src Inhibitor 1 is a potent, ATP-competitive and selective dual site Src tyrosine kinase inhibitor with IC50 values of 44 nM for Src and 88nM for Lck.

Product Specifications

CAS Number

179248-59-0

Target

Reference Standards; Src

Related Pathways

Others; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

COC1=CC2=NC=NC(NC3=CC=C(OC4=CC=CC=C4)C=C3)=C2C=C1OC

Molecular Formula

C22H19N3O3

Molecular Weight

373.40

References & Citations

[1]Tian G, et al. Structural determinants for potent, selective dual site inhibition of human pp60c-src by 4-anilinoquinazolines. Biochemistry. 2001 Jun 19;40 (24) :7084-91.|[2]Bain J, et al. The selectivity of protein kinase inhibitors: a further update. Biochem J. 2007 Dec 15;408 (3) :297-315.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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