ZINC13466751 (Standard)

ZINC13466751 (Standard) is the analytical standard of ZINC13466751 (HY-101028) . This product is intended for research and analytical applications. ZINC13466751 is a potent inhibitor of HIF-1α/von Hippel-Lindau interaction with an IC50 of 2.0 µM[1].

Product Specifications

CAS Number

[117953-17-0]

Target

HIF/HIF Prolyl-Hydroxylase; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cancer; Cardiovascular Disease

Smiles

O=C(N(C1=CC=CC=C1)N=C/2C)C2=N/NC3=CC=C(N4CCOCC4)C=C3

Molecular Formula

C20H21N5O2

Molecular Weight

363.41

References & Citations

[1]Xue X, et al. Discovery of novel inhibitors disrupting HIF-1α/von Hippel-Lindau interaction through shape-based screening and cascade docking. PeerJ. 2016 Dec 15;4:e2757.