ZINC13466751 (Standard)
ZINC13466751 (Standard) is the analytical standard of ZINC13466751 (HY-101028) . This product is intended for research and analytical applications. ZINC13466751 is a potent inhibitor of HIF-1α/von Hippel-Lindau interaction with an IC50 of 2.0 µM[1].
Product Specifications
CAS Number
[117953-17-0]
Target
HIF/HIF Prolyl-Hydroxylase; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cancer; Cardiovascular Disease
Smiles
O=C(N(C1=CC=CC=C1)N=C/2C)C2=N/NC3=CC=C(N4CCOCC4)C=C3
Molecular Formula
C20H21N5O2
Molecular Weight
363.41
References & Citations
[1]Xue X, et al. Discovery of novel inhibitors disrupting HIF-1α/von Hippel-Lindau interaction through shape-based screening and cascade docking. PeerJ. 2016 Dec 15;4:e2757.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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