CCT251236 (Standard)
CCT251236 (Standard) is the analytical standard of CCT251236. This product is intended for research and analytical applications. CCT251236 is an orally available pirin ligand from a heat shock transcription factor 1 (hsf1) phenotypic screen with an IC50 of 19 nM for inhibition of HSF1-mediated HSP72 induction.
Product Specifications
CAS Number
1693731-40-6
Target
HSP; Reference Standards
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Smiles
CC1=CC=C(NC(C2=CC(OCCO3)=C3C=C2)=O)C=C1NC(C4=CC(C=CC(OCCN5CCCC5)=N6)=C6C=C4)=O
Molecular Formula
C32H32N4O5
Molecular Weight
552.62
References & Citations
[1]Cheeseman MD, et al. Discovery of a Chemical Probe Bisamide (CCT251236) : An OrallyBioavailable Efficacious Pirin Ligand from a Heat ShockTranscription Factor 1 (HSF1) Phenotypic Screen. J Med Chem. 2017 Jan 12;60 (1) :180-201.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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