CXCR2-IN-1 (Standard)
CXCR2-IN-1 (Standard) is the analytical standard of CXCR2-IN-1. This product is intended for research and analytical applications. CXCR2-IN-1 is a central nervous system penetrant CXCR2 antagonist with a pIC50 of 9.3.
Product Specifications
CAS Number
1873376-49-8
Target
CXCR; Reference Standards
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Others
Field of Research
Inflammation/Immunology; Endocrinology
Smiles
ClC1=CC=C(NC(NC2=CC=CC(F)=C2Cl)=O)C(O)=C1S(=O)(C3CCN(C)CC3)=O
Molecular Formula
C19H20Cl2FN3O4S
Molecular Weight
476.35
References & Citations
[1]Xu H, et al. Discovery of CNS Penetrant CXCR2 Antagonists for the Potential Treatment of CNS Demyelinating Disorders. ACS Med Chem Lett. 2016 Feb 8;7 (4) :397-402.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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