α-Methylserotonin (maleate)

α-Methylserotonin maleate is a potent and selective agonist of 5-HT2 receptor. α-Methylserotonin maleate is an analogue of serotonin formed in vivo from α-Methyltryptophan. α-Methylserotonin maleate mediates the lymphatic smooth muscle contraction and prevents the up-regulation of serotonin-receptor-mediated phosphoinositide hydrolysis[1][2][3].

Product Specifications

CAS Number

[97469-12-0]

UNSPSC

12352200

Target

5-HT Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Purity

99.9

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC(/C=C\C(O)=O)=O.CC(N)CC(C1=C2)=CNC1=CC=C2O

Molecular Formula

C15H18N2O5

Molecular Weight

306.31

References & Citations

[1]Dobbins DE. Receptor mechanisms of serotonin-induced prenodal lymphatic constriction in the canine forelimb. Am J Physiol. 1998 Feb;274 (2) :H650-4.