IPAG (Standard)
IPAG (Standard) is the analytical standard of IPAG. This product is intended for research and analytical applications. IPAG is a potent sigma-1 receptor antagonist with a pKi of 4.3[1]. IPAG induces apoptosis[2].
Product Specifications
CAS Number
193527-91-2
Target
Reference Standards; Sigma Receptor
Related Pathways
Neuronal Signaling; Others
Field of Research
Cancer
Smiles
N=C(NC1=CC=C(I)C=C1)NC2[C@H]3C[C@H](C4)C[C@@H]2C[C@H]4C3
Molecular Formula
C17H22IN3
Molecular Weight
395.28
References & Citations
[1]James M Brimson, et al. Simple ammonium salts acting on sigma-1 receptors yield potential treatments for cancer and depression. Sci Rep. 2020 Jun 8;10 (1) :9251.|[2]Halley M Oyer, et al.Small-Molecule Modulators of Sigma1 and Sigma2/TMEM97 in the Context of Cancer: Foundational Concepts and Emerging Themes. Front Pharmacol. 2019 Oct 21;10:1141.|[3]Felix J Kim, et al. Inhibition of tumor cell growth by Sigma1 ligand mediated translational repression. Biochem Biophys Res Commun. 2012 Sep 21;426 (2) :177-82.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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