Protein kinase inhibitor H-7 (dihydrochloride) (Standard)
Protein kinase inhibitor H-7 (dihydrochloride) (Standard) is the analytical standard of Protein kinase inhibitor H-7 (dihydrochloride) . This product is intended for research and analytical applications. Protein kinase inhibitor H-7 dihydrochloride is a potent PKC (protein kinase C) inhibitor. At 100 μM, Protein kinase inhibitor H-7 dihydrochloride completely inhibits both TPA (skin tumour promoter, 12-O-tetradecanoylphorbol-13-acetate) and phospholipase C-induced ODC (ornithine decarboxylase) [1].
Product Specifications
CAS Number
108930-17-2
UNSPSC
12352005
Target
PKC; Reference Standards
Related Pathways
Epigenetics; Others; TGF-beta/Smad
Field of Research
Cancer
Smiles
O=S(C1=CC=CC2=C1C=CN=C2)(N3C(C)CNCC3)=O.[H]Cl.[H]Cl
Molecular Formula
C14H19Cl2N3O2S
Molecular Weight
364.29
References & Citations
[1]Fischer SM, et al. Mediation of phorbol ester-induced oxidant generation in murine epidermal cells by protein kinase C. Toxicol In Vitro. 1989;3 (3) :195-9.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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