Protein kinase inhibitor H-7 (dihydrochloride) (Standard)

Protein kinase inhibitor H-7 (dihydrochloride) (Standard) is the analytical standard of Protein kinase inhibitor H-7 (dihydrochloride) . This product is intended for research and analytical applications. Protein kinase inhibitor H-7 dihydrochloride is a potent PKC (protein kinase C) inhibitor. At 100 μM, Protein kinase inhibitor H-7 dihydrochloride completely inhibits both TPA (skin tumour promoter, 12-O-tetradecanoylphorbol-13-acetate) and phospholipase C-induced ODC (ornithine decarboxylase) [1].

Product Specifications

CAS Number

[108930-17-2]

UNSPSC

12352005

Target

PKC; Reference Standards

Related Pathways

Epigenetics; Others; TGF-beta/Smad

Field of Research

Cancer

Smiles

O=S(C1=CC=CC2=C1C=CN=C2)(N3C(C)CNCC3)=O.[H]Cl.[H]Cl

Molecular Formula

C14H19Cl2N3O2S

Molecular Weight

364.29

References & Citations

[1]Fischer SM, et al. Mediation of phorbol ester-induced oxidant generation in murine epidermal cells by protein kinase C. Toxicol In Vitro. 1989;3 (3) :195-9.