3,5-Dinitrocatechol (Standard)
3,5-Dinitrocatechol (Standard) is the analytical standard of 3,5-Dinitrocatechol. This product is intended for research and analytical applications. 3,5-Dinitrocatechol (OR-486) is a potent catechol-O-methyltransferase inhibitor, with an IC50 of 12 nM. 3,5-Dinitrocatechol can be used in the preparation of the molybdenum (VI) - 3,5-Dinitrocatechol complex[1][2][3].
Product Specifications
CAS Number
7659-29-2
Product Name Alternative
OR-486 (Standard) ; 3,5-Dinitropyrocatechol (Standard)
UNSPSC
12352005
Target
COMT; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
OC1=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C1O
Molecular Formula
C6H4N2O6
Molecular Weight
200.11
References & Citations
[1]Nissinen E, et, al. Inhibition of catechol-O-methyltransferase activity by two novel disubstituted catechols in the rat. Eur J Pharmacol. 1988 Aug 24;153 (2-3) :263-9. |[2]Yamaki F, et, al. Effects of Catecholamine Metabolites on Beta-Adrenoceptor-Mediated Relaxation of Smooth Muscle: Evaluation in Mouse and Guinea-Pig Trachea and Rat Aorta. Biol Pharm Bull. 2020;43 (3) :493-502. |[3]Stojnova K, et, al. Study on the Complex Equilibria of Molybdenum (VI) with 3,5-Dinitrocatechol and Ditetrazolium Salt. Acta Chim Slov. 2016;63 (3) :654-60.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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