Dilazep

Dilazep is an inhibitor of adenosine uptake. Dilazep has cerebral and coronary vasodilating action through enhancement of effect of adenosine. Dilazep also inhibits the ischemic damage, platelet aggregation, and membrane transport of nucleosides[1][2].

Product Specifications

CAS Number

[35898-87-4]

UNSPSC

12352005

Target

Nucleoside Transporters

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Smiles

O=C(C1=CC(OC)=C(OC)C(OC)=C1)OCCCN2CCN(CCCOC(C3=CC(OC)=C(OC)C(OC)=C3)=O)CCC2

Molecular Formula

C31H44N2O10

Molecular Weight

604.69

References & Citations

[1]Zhang Y, et al. Dilazep potentiation of adenosine-mediated superior mesenteric arterial vasodilation. J Pharmacol Exp Ther. 1991 Sep;258 (3) :767-71.|[2]Kawagoe J, et al. Effect of dilazep dihydrochloride against ischemia and reperfusion-induced disruption of blood-brain barrier in rats: a quantitative study. Naunyn Schmiedebergs Arch Pharmacol. 1992 Apr;345 (4) :485-8.