RX 801077 (hydrochloride) (Standard)
RX 801077 (hydrochloride) (Standard) is the analytical standard of RX 801077 (hydrochloride) (HY-100904) . This product is intended for research and analytical applications. RX 801077 hydrochloride (2 BFI) is a selective imidazoline I2 receptor (I2R) agonist with a Ki value of 70.1 nM. RX 801077 hydrochlorideshows anti-inflammation and neuroprotection. RX 801077 hydrochloride has the potential for the research of traumatic brain injury (TBI) [1][2].
Product Specifications
CAS Number
[89196-95-2]
Target
Imidazoline Receptor; Reference Standards
Related Pathways
Neuronal Signaling; Others
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
Cl[H].C1(C2=CC3=CC=CC=C3O2)=NCCN1
Molecular Formula
C11H11ClN2O
Molecular Weight
222.67
References & Citations
[1]Carpéné C, et al. Inhibition of amine oxidase activity by derivatives that recognize imidazoline I2 sites. J Pharmacol Exp Ther. 1995 Feb;272 (2) :681-8.|[2]Ni H, et al. 2-BFI Provides Neuroprotection Against Inflammation and Necroptosis in a Rat Model of Traumatic Brain Injury. Front Neurosci. 2019 Jun 26;13:674.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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