Norbinaltorphimine dihydrochloride (Standard)
Norbinaltorphimine dihydrochloride (Standard) is the analytical standard of Norbinaltorphimine dihydrochloride. This product is intended for research and analytical applications. Norbinaltorphimine dihydrochloride is a potent and selective κ opioid receptor antagonist.
Product Specifications
CAS Number
113158-34-2
Target
Opioid Receptor; Reference Standards
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
O[C@]12[C@]34[C@](OC5=C(O)C=CC(C[C@@]2([H])N(CC6CC6)CC4)=C35)([H])C7=C(C8=C([C@@](O9)([H])[C@]%10%11[C@](O)([C@](CC%12=C%11C9=C(C=C%12)O)([H])N(CC%13CC%13)CC%10)C8)N7)C1.Cl[H].Cl[H]
Molecular Formula
C40H45Cl2N3O6
Molecular Weight
734.71
References & Citations
[1]Birch PJ, et al. Norbinaltorphimine: antagonist profile at kappa opioid receptors. Eur J Pharmacol. 1987 Dec 15;144 (3) :405-8.|[2]Flax SM, et al. Effect of norbinaltorphimine on ∆⁹-tetrahydrocannabinol (THC) -induced taste avoidance in adolescent and adult Sprague-Dawley rats. Psychopharmacology (Berl) . 2015 Sep;232 (17) :3193-201.|[3]Jackson KJ, et al. Effects of the kappa opioid receptor antagonist, norbinaltorphimine, on stress and drug-induced reinstatement of nicotine-conditioned place preference in mice. Psychopharmacology (Berl) . 2013 Apr;226 (4) :763-8.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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