SAR-20347 (Standard)
SAR-20347 (Standard) is the analytical standard of SAR-20347 (HY-100895) . This product is intended for research and analytical applications. SAR-20347 is an inhibitor of TYK2, JAK1, JAK2 and JAK3 with IC50s of 0.6, 23, 26 and 41 nM, respectively.
Product Specifications
CAS Number
[1450881-55-6]
Target
JAK; Reference Standards
Related Pathways
Epigenetics; JAK/STAT Signaling; Others; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Field of Research
Cancer
Smiles
O=C(C1=C(NC2=CC=C(C(N3CCOCC3)=O)C=C2)OC(C4=C(F)C=CC=C4Cl)=N1)N
Molecular Formula
C21H18ClFN4O4
Molecular Weight
444.84
References & Citations
[1]Works MG, et al. Inhibition of TYK2 and JAK1 ameliorates imiquimod-induced psoriasis-like dermatitis by inhibiting IL-22 and the IL-23/IL-17 axis. J Immunol. 2014 Oct 1;193 (7) :3278-87.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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