Biotin-VAD-FMK (Standard)
Biotin-VAD-FMK (Standard) is the analytical standard of Biotin-VAD-FMK. This product is intended for research and analytical applications. Biotin-VAD-FMK is a cell permeable, irreversible biotin-labeled caspase inhibitor, used to identify active caspases in cell lysates.
Product Specifications
CAS Number
1135688-15-1
Target
Caspase; Reference Standards
Related Pathways
Apoptosis; Others
Field of Research
Cancer
Smiles
COC(C[C@@H](C(CF)=O)NC([C@H](C)NC([C@H](C(C)C)NC(CCCCCNC(CCCC[C@@H]1SC[C@H](N2)[C@@H]1NC2=O)=O)=O)=O)=O)=O
Molecular Formula
C30H49FN6O8S
Molecular Weight
672.81
References & Citations
[1]Li J, et al. Nitric oxide suppresses apoptosis via interrupting caspase activation and mitochondrial dysfunction in cultured hepatocytes. J Biol Chem. 1999 Jun 11;274 (24) :17325-33.|[2]Samraj AK, et al. Loss of caspase-9 reveals its essential role for caspase-2 activation and mitochondrial membranedepolarization. Mol Biol Cell. 2007 Jan;18 (1) :84-93.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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