Biotin-VAD-FMK (Standard)

Biotin-VAD-FMK (Standard) is the analytical standard of Biotin-VAD-FMK (HY-100894) . This product is intended for research and analytical applications. Biotin-VAD-FMK is a cell permeable, irreversible biotin-labeled caspase inhibitor, used to identify active caspases in cell lysates.

Product Specifications

CAS Number

[1135688-15-1]

Target

Caspase; Reference Standards

Related Pathways

Apoptosis; Others

Field of Research

Cancer

Smiles

COC(C[C@@H](C(CF)=O)NC([C@H](C)NC([C@H](C(C)C)NC(CCCCCNC(CCCC[C@@H]1SC[C@H](N2)[C@@H]1NC2=O)=O)=O)=O)=O)=O

Molecular Formula

C30H49FN6O8S

Molecular Weight

672.81

References & Citations

[1]Li J, et al. Nitric oxide suppresses apoptosis via interrupting caspase activation and mitochondrial dysfunction in cultured hepatocytes. J Biol Chem. 1999 Jun 11;274 (24) :17325-33.|[2]Samraj AK, et al. Loss of caspase-9 reveals its essential role for caspase-2 activation and mitochondrial membranedepolarization. Mol Biol Cell. 2007 Jan;18 (1) :84-93.