CD80-IN-3 (Standard)
CD80-IN-3 (Standard) is the analytical standard of CD80-IN-3. This product is intended for research and analytical applications. CD80-IN-3, a potent CD80 inhibitor, inhibits CD80/CD28 interaction with an EC50 of 630 nM and a Kd of 125 nM.
Product Specifications
CAS Number
486449-65-4
Target
CD28; Reference Standards
Related Pathways
Immunology/Inflammation; Others
Field of Research
Inflammation/Immunology
Smiles
FC1=C(NC=C2C3=NN(C4=CC=C(C(O)=O)C=C4)C2=O)C3=CC=C1
Molecular Formula
C17H10FN3O3
Molecular Weight
323.28
References & Citations
[1]Huxley P, et al. High-affinity small molecule inhibitors of T cell costimulation: compounds for immunotherapy. Chem Biol. 2004 Dec;11 (12) :1651-8.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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