CD80-IN-3 (Standard)

CD80-IN-3 (Standard) is the analytical standard of CD80-IN-3 (HY-100891) . This product is intended for research and analytical applications. CD80-IN-3, a potent CD80 inhibitor, inhibits CD80/CD28 interaction with an EC50 of 630 nM and a Kd of 125 nM.

Product Specifications

CAS Number

[486449-65-4]

Target

CD28; Reference Standards

Related Pathways

Immunology/Inflammation; Others

Field of Research

Inflammation/Immunology

Smiles

FC1=C(NC=C2C3=NN(C4=CC=C(C(O)=O)C=C4)C2=O)C3=CC=C1

Molecular Formula

C17H10FN3O3

Molecular Weight

323.28

References & Citations

[1]Huxley P, et al. High-affinity small molecule inhibitors of T cell costimulation: compounds for immunotherapy. Chem Biol. 2004 Dec;11 (12) :1651-8.