BRCA1-IN-2 (Standard)
BRCA1-IN-2 (Standard) is the analytical standard of BRCA1-IN-2. This product is intended for research and analytical applications. BRCA1-IN-2 (compound 15) is a cell-permeable protein-protein interaction (PPI) inhibitor for BRCA1 with an IC50 of 0.31 μM and a Kd of 0.3 μM, which shows antitumor activities via the disruption of BRCA1 (BRCT) 2/protein interactions[1].
Product Specifications
CAS Number
1622262-55-8
Target
PARP; Reference Standards
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; Others
Field of Research
Cancer
Smiles
O=C(N[C@@H](COP(O)(O)=O)C(NCC(NCCCCC1=CC=CC=C1)=O)=O)CCC2=CNC3=C2C=CC=C3
Molecular Formula
C26H33N4O7P
Molecular Weight
544.54
References & Citations
[1]Na Z, et al. Protein-Protein Interaction Inhibitors of BRCA1 Discovered Using Small Molecule Microarrays. Methods Mol Biol. 2017;1518:139-156.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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