PCO371 (Standard)

PCO371 (Standard) is the analytical standard of PCO371 (HY-100856) . This product is intended for research and analytical applications. PCO371 is an orally active full agonist of parathyroid hormone receptor 1 (PTHR1), with no effect on PTH type 2 receptor.

Product Specifications

CAS Number

[1613373-33-3]

Target

PTHR; Reference Standards

Related Pathways

GPCR/G Protein; Others

Field of Research

Endocrinology

Smiles

FC(F)(F)OC1=CC=C(C2=NC3(CCN(S(CCC4=C(C)C=C(N5C(NC(C5(C)C)=O)=O)C=C4C)(=O)=O)CC3)C(N2)=O)C=C1

Molecular Formula

C29H32F3N5O6S

Molecular Weight

635.65

References & Citations

[1]Tamura T, et al. Identification of an orally active small-molecule PTHR1 agonist for the treatment of hypoparathyroidism. Nat Commun. 2016 Nov 18;7:13384.