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ER-000444793 (Standard)

ER-000444793 (Standard) is the analytical standard of ER-000444793. This product is intended for research and analytical applications. ER-000444793 is a potent inhibitor of mitochondrial permeability transition pore (mPTP) opening. ER-000444793 inhibits mPTP with an IC50 of 2.8 μM.

Product Specifications

CAS Number

792957-74-5

Target

Mitochondrial Metabolism; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Smiles

O=C(NC1=C(CC2=CC=CC=C2)C=CC=C1)C(C3=CC=CC=C3N4)=CC4=O

Molecular Formula

C23H18N2O2

Molecular Weight

354.40

References & Citations

[1]Briston T, et al. Identification of ER-000444793, a Cyclophilin D-independent inhibitor of mitochondrial permeability transition, using a high-throughput screen in cryopreserved mitochondria. Sci Rep. 2016 Nov 25;6:37798.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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