ER-000444793 (Standard)
ER-000444793 (Standard) is the analytical standard of ER-000444793 (HY-100852) . This product is intended for research and analytical applications. ER-000444793 is a potent inhibitor of mitochondrial permeability transition pore (mPTP) opening. ER-000444793 inhibits mPTP with an IC50 of 2.8 μM.
Product Specifications
CAS Number
[792957-74-5]
Target
Mitochondrial Metabolism; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Smiles
O=C(NC1=C(CC2=CC=CC=C2)C=CC=C1)C(C3=CC=CC=C3N4)=CC4=O
Molecular Formula
C23H18N2O2
Molecular Weight
354.40
References & Citations
[1]Briston T, et al. Identification of ER-000444793, a Cyclophilin D-independent inhibitor of mitochondrial permeability transition, using a high-throughput screen in cryopreserved mitochondria. Sci Rep. 2016 Nov 25;6:37798.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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