(RS) - (Tetrazol-5-yl) glycine
(RS) - (Tetrazol-5-yl) glycine (D, L- (tetrazol-5-yl) glycine) is a highly potent and selective N-methyl-D-aspartate (NMDA) receptor agonist[1]. (RS) - (Tetrazol-5-yl) glycine has EC50s of 99 nM, 1.7 μM for GluN1/GluN2D and GluN1/GluN2A, respectively[2]. (RS) - (Tetrazol-5-yl) glycine induces seizure responses and Fos in mice[3].
Product Specifications
CAS Number
138199-51-6
Product Name Alternative
D, L- (tetrazol-5-yl) glycine; LY 285265
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
IGluR
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Purity
96.53
Solubility
H2O : 5 mg/mL (ultrasonic)
Smiles
O=C(O)C(N)C1=NNN=N1
Molecular Formula
C3H5N5O2
Molecular Weight
143.10
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NMDA Receptor
Available Sizes
Frequently Asked Questions
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