5,7-Dichlorokynurenic acid (Standard)
5,7-Dichlorokynurenic acid (Standard) is the analytical standard of 5,7-Dichlorokynurenic acid. This product is intended for research and analytical applications. 5,7-Dichlorokynurenic acid (5,7-DCKA) is a selective and competitive antagonist of the glycine site on NMDA receptor with a KB of 65 nM. 5,7-Dichlorokynurenic acid, a derivative of kynurenic acid, reduced NMDA-induced neuron injury in rat cortical cell cultures[1].
Product Specifications
CAS Number
[131123-76-7]
Product Name Alternative
5,7-DCKA (Standard)
UNSPSC
12352005
Target
IGluR; Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
O=C(C1=NC2=CC(Cl)=CC(Cl)=C2C(O)=C1)O
Molecular Formula
C10H5Cl2NO3
Molecular Weight
258.06
References & Citations
[1]D McNamara, et al. 5,7-Dichlorokynurenic acid, a potent and selective competitive antagonist of the glycine site on NMDA receptors. Neurosci Lett. 1990 Nov 27;120 (1) :17-20.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Curated Selection
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